Mitochondrial ROS regulate oxidative damage and mitophagy but not age-related muscle fiber atrophy
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Mitochondrial ROS regulate oxidative damage and mitophagy but not age-related muscle fiber atrophy
Age-related loss of skeletal muscle mass and function is a major contributor to morbidity and has a profound effect on the quality of life of older people. The potential role of age-dependent mitochondrial dysfunction and cumulative oxidative stress as the underlying cause of muscle aging remains a controversial topic. Here we show that the pharmacological attenuation of age-related mitochondri...
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ژورنال
عنوان ژورنال: Scientific Reports
سال: 2016
ISSN: 2045-2322
DOI: 10.1038/srep33944